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Chronic Kidney Disease in 2025: From Silent Epidemic to Treatable Risk State
Andrew Kowalski, MD, FASN The Scale of the Problem CKD has quietly emerged from the shadows of nephrology to become a defining challenge in global health. Current estimates suggest that approximately 850 million people worldwide live with CKD, with roughly 4 million receiving dialysis or living with a kidney transplant (Herrington et al., 2025). These numbers are staggering, but what makes them truly alarming is the trajectory: based on current trends, CKD is projected to be


Mitochondrial Dysfunction in Chronic Kidney Disease: A Missing Link in Nephrology?
Andrew Kowalski, MD, FASN The mitochondria, often described as the “powerhouses” of our cells, provide the energy required for nearly every biological process known. In the kidney, which is one of the most energy-demanding organs in the body, mitochondria play an especially critical role. Every filtration, reabsorption, and secretion step along the nephron requires a steady supply of ATP (adenosine triphosphate), and this demand makes kidney tissue uniquely vulnerable to mit


🧠 Magnesium and Kidney Disease: What You Should Know
Carla Valencia, MD Introduction When you think about kidney health, you probably hear a lot about potassium, sodium, or phosphorus, but magnesium is just as important! This small but mighty mineral plays a significant role in how our bodies function , and for individuals with CKD , maintaining the right magnesium balance can make a substantial difference. 🌿 What Is Magnesium and Why Is It Important? Magnesium is a mineral that helps your body in many ways: • Keeps your
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