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Chronic Kidney Disease in 2025: From Silent Epidemic to Treatable Risk State
Andrew Kowalski, MD, FASN The Scale of the Problem CKD has quietly emerged from the shadows of nephrology to become a defining challenge in global health. Current estimates suggest that approximately 850 million people worldwide live with CKD, with roughly 4 million receiving dialysis or living with a kidney transplant (Herrington et al., 2025). These numbers are staggering, but what makes them truly alarming is the trajectory: based on current trends, CKD is projected to be
Andrew Kowalski
3 hours ago7 min read


Mitochondrial Dysfunction in Chronic Kidney Disease: A Missing Link in Nephrology?
Andrew Kowalski, MD, FASN The mitochondria, often described as the “powerhouses” of our cells, provide the energy required for nearly every biological process known. In the kidney, which is one of the most energy-demanding organs in the body, mitochondria play an especially critical role. Every filtration, reabsorption, and secretion step along the nephron requires a steady supply of ATP (adenosine triphosphate), and this demand makes kidney tissue uniquely vulnerable to mit
Andrew Kowalski
Nov 97 min read


🧠 Magnesium and Kidney Disease: What You Should Know
Carla Valencia, MD Introduction When you think about kidney health, you probably hear a lot about potassium, sodium, or phosphorus, but magnesium is just as important! This small but mighty mineral plays a significant role in how our bodies function , and for individuals with CKD , maintaining the right magnesium balance can make a substantial difference. 🌿 What Is Magnesium and Why Is It Important? Magnesium is a mineral that helps your body in many ways: • Keeps your
Carly Valencia-Ochoa, MD
Nov 83 min read


☀️ Vitamin D and Kidney Disease: What You Need to Know
Carla Valencia, MD Introduction Vitamin D is not just for strong bones, it helps many parts of the body, including the kidneys. For individuals with CKD, maintaining a balanced vitamin D level is particularly crucial . This guide explains why vitamin D is important, the different types of vitamin D, when and how doctors may treat low vitamin D levels, and what the research says. 🌟 What does vitamin D do in the body? • Helps the body use calcium and phosphorus for strong bo
Carly Valencia-Ochoa, MD
Nov 84 min read


Understanding the Importance of Monitoring Your Albumin-to-Creatinine Ratio for Kidney Health
Andrew Kowalski, MD, FASN Our kidneys work tirelessly every day to filter waste, remove toxins, and keep the body’s fluid and mineral balance in check. However, kidney disease often develops silently, showing few or no symptoms until it’s already advanced. This is why regular testing, especially for people at risk, is crucial. One of the simplest yet most powerful tests for early kidney damage is the albumin-to-creatinine ratio (ACR) test. Understanding what this test measur
Andrew Kowalski
Nov 25 min read


The New Frontier in Kidney Care Break throughs That Could Transform Nephrology
Andrew Kowalski, MD, FASN Kidney disease affects over 850 million people worldwide —more than diabetes or cancer, yet it often goes unnoticed until significant damage has occurred. For decades, treatment options remained limited to already advanced CKD patiens with options like dialysis and transplantation, with little hope for disease reversal. Fortunately, this reactive approach to Kidney disease is rapidly changing . Over the past few years, scientists have turned once, t
Andrew Kowalski
Nov 28 min read


Benefits & Misconceptions of Creatine Supplementation
Andrew Kowalski, MD FASN Introduction Creatine monohydrate (commonly referred to simply as “creatine”) is one of the most-studied dietary supplements. It is naturally synthesized in the human body (mainly in the liver and kidneys) and also obtained via intake of protein-rich foods (especially red meat and fish). While it is widely used by athletes for muscle performance enhancement, its benefits extend beyond muscle strength into cognitive function (brain) and, more unexpect
Andrew Kowalski
Nov 29 min read


Creatine and Protein Powder: More Info Before Starting these Supplements
Carly Valencia-Ochoa, MD Creatine (the exercise supplement) What it is and why people take it Creatine monohydrate helps build muscle strength and is widely used by athletes and older adults to preserve muscle mass, but also has function in preserving brain health. What it does to the labs and kidneys Creatine breaks down into creatinine , so taking creatine commonly ↑ increases serum creatinine. That can make eGFR appear worse, even if kidney function hasn’t changed. Major
Carly Valencia-Ochoa, MD
Oct 104 min read
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